Chromosome

noun (countable)
/ˈkrəʊməsəʊm/
A chromosome is a thread-like structure of nucleic acid (DNA) and protein (histones) found in the nucleus of eukaryotic cells that carries genetic information in the form of genes arranged linearly along its length. Humans have 46 chromosomes (23 pairs); prokaryotes typically have a single circular chromosome. The sex chromosomes (XX = female, XY = male) determine biological sex; numerical abnormalities (aneuploidy) or structural rearrangements cause genetic disorders. India's Rashtriya Bal Swasthya Karyakram (RBSK) screens newborns for chromosomal disorders including Down syndrome (trisomy 21) and Turner syndrome (45, X).

✍️ Usage in a UPSC answer

India's Pre-Conception and Pre-Natal Diagnostic Techniques (PCPNDT) Act, 1994, regulates chromosomal and genetic testing to prevent sex-selective abortion, reflecting the dual role of chromosomal science in both medical diagnosis and social policy.

Synonyms

chromatin threadchromatin bodykaryosome (dated)genetic strand

Antonyms

plasmid (extrachromosomal element)cytoplasmic DNA (mitochondrial/chloroplast)

🌱 Word Family

chromosomal (adjective), chromatin (noun), chromatid (noun), chromosome pair (noun phrase), autosome (noun), sex chromosome (noun phrase)

🔡 Root

Greek khrōma = colour + sōma = body (named because these structures were stained with dyes and appeared coloured under the microscope)

📜 Etymology

The term was coined by German anatomist Heinrich Wilhelm von Waldeyer-Hartz in 1888 from Greek khrōma (colour) and sōma (body), describing the deeply staining thread-like bodies visible in dividing cells under aniline dyes. Walther Flemming had described the structures in 1878 but called them 'chromatin'. The -some suffix (from sōma, body) recurs across biology in 'ribosome', 'lysosome', and 'centrosome', all denoting discrete sub-cellular bodies.

🧠 Memory Hook

Chromosome = khrōma (colour) + sōma (body) — a 'coloured body'. Scientists named it because these structures soak up dye and appear as vivid coloured threads under the microscope. Think: when you stain a cell, the chromosomes COLOUR themselves brightly, standing out as coloured bodies.

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